With Makeshift Trap (Improved Timer. + Net.) and some other tricks (Lure/Lure, Bait and Switch, "Get over here!"/"Get over here!", Predator or Prey) you can have your own antimatter singularity for 6 less XP than the boring vanilla Poisonous. + Explosive Device. combo.

Probably still only worth it in Calvin, but this way I think you can truly maximize the output of "I'll see you in hell!".

(I guess it's also viable in Tommy since he can easily take the trauma.)

Besides the obvious curse synergies, this is a great card for the low-/zero-difficulty playstyle, using Makeshift Trap, Gumption, and Oops!/Oops!.

You can also pair it with Justify the Means, Three Aces, or, if you do care about the curses, drop a Favor of the Moon in the player window during the skill test.

Thinking of Preston Fairmont.

Norman Withers and The Harbinger say hi. While not game-breaking, the interactions between empty space and this investigator can lead to interesting and unique edge (of the universe) cases.

Wake Azathoth, they said. It will be fun, they said.

2x Ariadne's Twine 1x Cryptic Grimoire 1x Dr. Milan Christopher

Congratulations, now you get 1 actionless Investigate that charges your Myconid every single round. The Myconids seem likely to get Taboo'd pretty quickly to me, especially the Sentient Strain. It is incredibly easy to game these things out and trivialize an entire scenario.

This card is quite a good reward if you're playing this mission as a side scenario, especially in seeker. Doesn't take up a slot, has situational obstacle removal and most of all it allows a main cluer to delete enemies in a single check. With higher education and some good economy cards (milan, crack the case) it becomes rather trivial to remove several enemies over the course of the scenario. Bonus points if you're Kate for that extra science asset.