Sadly, the problem with this card is that you can't pitch it for +1 on a skill test when you first start a campaign. So, if you draw it immediately after your mulligan it's not mega doo doo. Without that it's in a very awkward spot which will likely make this unplayable for vast majority of characters/campaigns (although there are some that you should really take it see SPOILERS below).

For example, if it had just a single wild icon it would become actually useable at lvl 0 as pitching it for a +1 skill test early on would have made it seen some play in some decks especially mill decks like Minh or Patrice both of which are action starved and like pitching wild icon cards. Then when the survivor gets some early exp they can do things like pitch it on the Hunting Jacket for a resource and save it for the final agenda.

SPOILERS YOU HAVE BEEN WARNED

First column is scenario number, second is number of rounds you would have to wait if you drew it in your opening hand this counts all agendas before the "final" agenda, and third is the number of rounds you could play it before the game ends. Lower first number and higher second number = good scenario for End of the Road.

Some asterisks:

• There are some agendas that are "infinite" or dependent on what the investigators/act does in which case I use the base doom or make an estimate based on my experiences with the scenario.
• There is a question of what is a “final agenda” because it gets weird with things especially with recent campaigns like Edge of the Earth/Scarlet Keys/Hemlock with act/agendas that replace the agenda deck. Generally they don’t impact things too much on the overall assessment and you can argue at your table if you count it or not until an official ruling is added here. Honestly End of the Road needs as much help as it can get so for the below numbers I counted in favor of it being able to trigger since the current agenda is the “final” agenda in the agenda deck at the time of play.

The Gathering ( 1 / 5 )

Really only decent in Midnight Masks if you want to give it a newbie to have fun with.

The Dunwich Legacy ( 0 / 5 )

LOL

The Path to Carcosa ( 1 / 5 )

You got some hits like 2nd and 6th scenario, but a lot of doo doo in between.

The Forgotten Age ( 1 / 5 )

Only a 1 because its decent in the first 2 scenarios. But, it really fails to deliver after them so if you add it remember to remove it after the first 2 scenarios. However, the first 2 scenarios are very much get ahead stay ahead and potentially holding onto End of the Road for 6 rounds is a bit of a pain.

The Circle Undone ( 2 / 5 )

Really the only bummers are 3rd and final. First campaign with a 100% uptime scenario on the 7th scenario so if you have adaptable good to slot it in then.

The Dream-Eaters Part A ( 5 / 5 )

Its only a 5 because of the 1st scenario and accelerated exp, grab it for the first scenario then immediately dump it with your double digit exp.

The Dream-Eaters Part B ( 1 / 5 )

Its just not good enough in the early scenarios to get to the payoff in the third scenario.

The Innsmouth Conspiracy ( 0 / 5 )

Yeah... unless you're a masochist its terrible somehow worse on avg. here than Dunwich.

The Edge of the Earth ( 3 / 5 )

This is funny the worse you do in the opening scenario(s) the better End of the Road becomes. Since End of the Road will more often be a dead card in your hand in the opening scenario it itself helps contributes with getting a worser outcome for your group so it can shine further down. It's also good in the endgame if you count replacing agendas.

The Scarlet Keys ( 1 / 5 )

Release expansion and not a good showing the first scenario has a long time before the final agenda, and since some players will not hit the 100% scenarios based on where they go it can be a full campaign with End of the Road in the gutter.

The Feast of Hemlock Vale ( 4 / 5 )

Seems like End of the Road should have been released with Hemlock as Preludes really carry it. An additional action, card, and resource can be the difference on a succesful Resident objective and/or preparing for the day scenario. Most of the scenarios have low early doom agendas and high final agenda doom. Just make sure to ditch it before the final scenario otherwise you'll regret it.

TLDR: When is it good to include?

Base Deck:

• The Dream-Eaters Part A ditch it after the first scenario since you start with the final agenda.
• Feast of Hemlock Vale ditch it before the final scenario.

Adaptable:

• Circle Undone has the first 100% playability in the 7th scenario in which the scenario begins in the final agenda.
• Edge of the Earth has some 100% scenarios especially if you crash out in the opening scenario(s).
• Scarlet Keys has two 100% scenarios: Sanguine Shadows, Dogs of War.

Very tough card to rate as it's extremely scenario/campaign dependent before you even consider how it fits into your deck. Obviously strong when you can actually play it, but how often does that happen? How often is the scenario result decided before this becomes playable?

Personally, I think this card is a bit of a trap in most cases. In a lot of scenarios, the toughest part of the game comes early, and the result usually comes from which way the game started snowballing. Either you easily handle what the encounter deck throws at you, get your engine running, and cruise to victory, or you suffer some setbacks, waste resources, and get stuck until your doom is assured. This card isn't needed to win in the first case, and does little to prevent the latter.

Because it has no icons, this is probably best slotted in for fun in investigator with discard for benefit ability, like Wendy Adams or "Ashcan" Pete.

And I guess with this card it is now official that the amount of remaining agenda is an open information, AFAIK it was not anywhere in the rule. (In blind runs I used to not telling the rest of the table would the game over or not after the current agenda, I being the setup person.)